- because their quality is not good enough

The majority of supplements with vitamins and minerals fails to extend life or protect against cardiovascular disease, although fish oil does seem to have a good effect, according to a large review from John Hopkins University. On the other hand, a Danish study shows that blood levels of vitamin D are crucial for a person’s expected lifespan, and a groundbreaking Swedish study shows that patented supplements with Q10 and selenium benefit older people by improving their cardiac health and reducing cardiovascular mortality by 50%. What matters is to use supplements that contain nutrients in the right quantity, which have a proper quality and can be absorbed by the body. In the following, you can read more about the different studies and learn how you can improve your heart health and increase your chances of a longer life.

An international science team from the University of Surrey in England has found a link between low selenium levels in the soil and the risk od COVID-19 infections becoming lethal. Professor Margaret Rayman, who headed the study, has spent decades studying the global lack of selenium that is known to impair the ability of the immune system to tackle virus infections and new epidemics. The farmlands in large parts of the world, including Europe and China, are low in selenium, and it is vital to have more focus on this essential nutrient.

The number of seniors in the world is growing. It hardly comes as a surprise that old people wish to stay mentally and physically fit and enjoy every minute of the of life. Nonetheless, many middle-aged and older people feel tired and lethargic, or they suffer from chronic diseases that impair their quality of life and are associated with shorter life expectancy. In his book, Coenzyme Q10 – An Insider’s Guide, Dr. William V. Judy looks closer at how Q10 is able to delay the ageing process at a cellular level by increasing energy levels, supporting heart health, and preventing atherosclerosis and other chronic diseases that are linked to ageing. Combined supplementation with Q10 and selenium can even delay the risk of early death by over 50 percent. Dr. Judy makes a point of saying how important it is to choose pharmaceutical-grade Q10 that the body can absorb and utilize.

- and increases the risk of degenerative disease and early death

It is commonly known that degenerative diseases such as cardiovascular disease, diabetes, kidney ailments, and liver diseases are often linked to poor quality of life and shorter lifespan. Supplementing with Q10, possibly in combination with selenium yeast, may have a positive influence on the mentioned conditions and lower your risk of premature death by as much as 50 percent or more. In fact, Q10 can help delay the ageing processes by protecting the heart, cardiovascular system, and cells, according to a large review article published online by NCBI (National Center for Biotechnology Information). As mentioned in this article, it is essential to use supplements that are pharmaceutical-grade in order to ensure proper absorption in blood and tissue.

– and could even make them more dangerous

Selenium is of vital importance to a strong immune defense. Still, selenium deficiency is a common problem and it increases the risk of viral infections such as influenza and the coronavirus from China, which is feared to turn into a global pandemic. It is a problem that selenium deficiency in infected animals and humans causes the virus to mutate and become more aggressive. Because of selenium’s important role as a powerful antioxidant, being deficient of this micronutrient may leave the body vulnerable to oxidative stress, which can cause tissue damage and complicate the virus infection. It is therefore important to get enough selenium at all times, as it also increases our resistance towards other viral infections such as herpes, HIV, and hepatitis, according to an article published in Nutrients.

Lack of selenium, an essential trace element, may cause thyroid disorders, cardiovascular disease, virus infections, AIDS, infertility, neurological disturbances, and cancer. An estimated one billion people worldwide are selenium-deficient. This is mainly a result of nutrient-depleted soil, which is a real problem in places like Europe. For decades, scientists have been warning about this problem, and a lot suggests that we need more than the officially recommended intake to protect ourselves effectively against disease, according to a review article published in StatPearls.

- with links to cancer, Parkinson’s disease, and other neurological disorders

The mitochondria are the powerhouses of our cells that churn out energy in a process that involves oxygen, Q10, selenium, and other nutrients. Around 100 years ago, the German Nobel Prize winner, Professor Otto Warburg, demonstrated that even if cancer can be caused by a number of secondary factors, there is only one primary cause: alterations in the mitochondrial oxygen turnover. In his recent book, Tripping over the Truth, molecular biologist Travis Christoffersen describes how contemporary scientists confirm Warburg’s theories and says that we need to look at prevention and cancer treatment from an entirely different angle. Other studies show that Parkinson’s disease, migraine, senility, chronic fatigue, fibromyalgia, epilepsy, and other neurological disorders may be rooted in defects of the mitochondria that have many other functions besides delivering energy. It is therefore vital to take care of the mitochondria throughout life. You can read more about the ketogenic diet that optimizes mitochondrial energy turnover in different mitochondrial diseases.

Selenium is a trace element that supports over 30 essential selenoproteins, which have numerous functions. For the first time ever, a study of Mexican children reveals that lack of selenium delays the growth of pubic hairs and the development of sex organs in boys. It is a known fact that the agricultural soil in Mexico is low in selenium and that affects the entire food chain. The same is the case in Europe, for which reason farmers for decades have supplemented livestock with selenium as a way of improving fertility and preventing a number of deficiency problems. The big question is to what extent can selenium deficiency problems explain the impaired sperm quality that has been observed among young men? An estimated 500 million to one billon people worldwide get too little selenium from their diet.

Infertility affects around one in seven couples. WHO considers it a global health problem. One of the leading causes is impaired semen quality, and Danish, Norwegian, and German men have lower sperm quality than any other male populations. Impaired sperm quality may be a result of an unhealthy lifestyle with stress, tobacco, stimulants, and hormone-disrupting compounds. On the other hand, scientists from Mexico have found that supplements of zinc, selenium, Q10, and omega-3 have an effect on the number of sperm cells and their quality. Other studies show that zinc and selenium protect sperm cells and are important for testosterone levels.

Selenium is an essential trace element that is important for the immune defense, metabolism, fertility, nervous system, and cancer prevention. An estimated one billion people worldwide are believed to be selenium-deficient. Because European agricultural soil is low in selenium, we Europeans are more exposed than others. It appears that selenium deficiencies increase our risk of many acute, chronic, and life-threatening diseases, and the official recommendations for daily intake are too low, according to a new article about selenium deficiency, which is published in the scientific American database NCBI (National Center for Biotechnology Information).

- but specific nutrients protect you

People, who eat nutrient-depleted diets, have an increased risk of contracting cancer, according to a French study that is published in PLoS Medicine. The scientists therefore recommend labeling food to help consumers make healthier choices. In the Nordic countries, we already have the “Keyhole label” on certain healthy food items, but even if you follow the official dietary guidelines, it may be difficult to get enough vitamin D and selenium, both of which are nutrients with several anti-cancer mechanisms.

Perhaps so. More and more studies reveal that it helps to take large quantities of Q10 and a vitamin B3 derivate. Q10 and vitamin B3 are both essential for the body’s energy turnover, which takes place inside the mitochondria of the cells. A more recent study shows that taking supplements of the mentioned nutrients can also have a positive effect on the heart, which is the body’s central motor.

Earlier studies have found a link between low selenium and overweight, but only few and limited studies have investigated this connection in children. Therefore, Chinese researchers wanted to take a closer look, and selenium levels in nail clippings give a rather accurate picture of the body’s general selenium status. Selenium deficiency is common in many parts of the world, including parts of China and Europe.

- and selenium deficiencies are widespread

An estimated 500,000 Danes suffer from some kind of thyroid disorder, the most common of which is Hashimoto’s disease, which slows down your metabolism. The formation and activation of thyroid hormones depend on iodine and selenium, and it is essential that the two nutrients are properly balanced. Having too little or too much iodine increases your risk of Hashimoto’s disease, and the same is the case with selenium, a nutrient that many people lack.
Some of the problems that are seen in people with slow metabolism are extreme fatigue, weight gain, constipation, cold sensitivity, swollen neck, and dry skin. The symptoms can vary, however, and many people still have not been given the proper diagnosis.
Medical therapy with thyroid hormones will not necessarily solve the problem. In fact, as many as 20 percent of patients actually feel worse, although their blood tests appear to be normal. It is therefore important to focus more in the role of iodine and selenium in the metabolism.

Selenium is a constituent of at least 25 essential proteins (selenoproteins), including several antioxidants that protect cells against oxidative stress and disease. A team of researchers from Munich in Germany has mapped out the mechanisms, which the selenium-containing antioxidants use to protect neurons in the brain against cell death. The scientists see a whole new potential with selenium because of its ability to protect against neurological disorders and cancer. It is problematic, however, that we have widespread selenium deficiency in our part of the world. Even if you stick with the official dietary guidelines, it is very difficult to get enough selenium to saturate all the different selenoproteins.

- thereby contributing to far fewer cases of cardiac death

Q10 and selenium are powerful antioxidants that are important for the heart, cardiovascular system, and the energy turnover. As we grow older, our endogenous Q10 synthesis decreases, and many people lack selenium. A Swedish study has shown that older people who take supplements of Q10 and selenium have a 50 percent lower cardiovascular death rate. Another (more recent) Swedish study shows that Q10 and selenium also increase elderly peoples’ levels of IGF-1, a hormone with many functions in the body. The scientists assume that this helps reduce the risk of cardiac death among elderly people.

Even if you eat a healthy and balanced diet, it can be difficult to get enough selenium because of climate changes and nutrient depletion of the soil, especially in Europe. This was shown in a study conducted by Swiss scientists. Selenium is very important for the immune system, but how much do we need to be optimally protected against infections? There also appears to be a connection between widespread selenium deficiency and the increased rate of cancer.

- but dietary and lifestyle changes make a difference

Approximately one in seven couple is childless. Although there can be many underlying causes, poor sperm quality is an increasing problem. It may be caused by a lack of certain nutrients and exposure to different environmental factors, but, fortunately, it possible to improve sperm quality and increase the chances of conception by means of relevant dietary adjustments and the use of specific supplements. New research shows that epigenetic factors (factors that affect the environment of the sperm cell) determine sperm health and are therefore crucial for activating the genes of the sperm cell so the fetus can develop.

An international team of researchers has just completed a huge study of the possible link between maternal DNA, selenium deficiency, and preterm labor. Earlier studies have shown that women with low blood selenium have an increased risk of preterm birth and that selenium supplementation may lower that risk. A problem in that respect is that climate changes and soil depletion may increase the risk of selenium deficiencies, especially in Europe.

Climate changes and soil depletion increase the risk of selenium deficiency, especially in Europe as shown by Swiss scientists. Selenium is an essential nutrient, and existing studies clearly show that low selenium intake increases the risk of cancer, metabolic disorders, impaired immunity, poor sperm quality, and atherosclerosis. Selenium deficiencies are therefore to be taken seriously and should be prevented one way or another. A good way to get enough of the nutrient is by taking a high-quality selenium supplement.

Ageing processes are associated with loss of muscle mass and impaired physical performance, both of which tend to lower quality of life. It is commonly known that coenzyme Q10 plays a significant role in cellular energy turnover and protects against oxidative stress. Now, two independent cohort studies even show a relation between the body’s Q10 status and muscle strength. Earlier research even suggests that Q10 supplements may help older people develop more youthful muscle fibers. Individuals who take cholesterol-lowering statins are advised to take Q10 supplements.

All our cells contain different selenium compounds that support a number of vital functions, and which have several cancer-fighting mechanisms. As an antioxidant, selenium prevents iron from developing some of the most harmful free radicals that can damage cellular DNA and lead to uncontrolled cell division. This is why a selenium deficiency combined with excess iron is a lethal cocktail. Although iron is essential, it is vital that we do not get too much. It is also important to get plenty of selenium from food and/or supplements and in a form that the body can absorb and utilize in each and every cell in order to be properly protected against cancerous substances.

According to a Japanese study, some people with Parkinson’s disease may find that coenzyme Q10 helps to relieve their symptoms. Q10 occurs in two forms, both of which have vital functions, but the scientists observed that only the one form had a positive effect on Parkinson’s disease. Nonetheless, when supplementing with Q10, both forms are equally good. What matters is that the active compound can be absorbed. Once it has been absorbed, the body can shift from one form to the other, a process that also requires selenium.

Selenium is crucial for your thyroid function, immune system, cardiovascular system, and even for preventing cancer. Fish and shellfish are among the best selenium sources, but even 200 grams of fish and shellfish five days a week won’t do the trick, according to a Danish selenium study. What makes it even more difficult to obtain optimal amounts of this nutrient is that the agricultural soil in large parts of Europe is stripped of vital nutrients like selenium. Margaret P. Rayman, one of Europe’s leading experts on selenium, says that there is a direct link between the decreasing selenium intake and the increasing rate of cancers, rheumatism, infertility, and numerous other health problems. The question is, how do we humans get enough selenium?

- and lacking certain nutrients may play a vital role

New figures from the cancer database, Nordcan, reveal that Danish women hold the record in cancer prevalence, and both sexes still have the lowest cancer survival rate among the Nordic countries. Experts claim that this is linked to our lifestyle. However, cancer even occurs among people with healthy lifestyles, and international studies suggest that modern diets tend to lack optimal amounts of selenium, vitamin D and omega-3, all of which have cancer-preventive properties. Research also points to melatonin, also known as the sleep hormone.

Q10 is involved in the energy turnover in all cells. The highest concentration of the compound is found in the heart, as this muscle needs to pump day and night and to supply muscle cells with more blood when we are physically active. The cellular energy turnover takes place inside some minute powerhouses called mitochondria. A Danish-Swedish study has shown that the mitochondria in the muscle cells of top-notch athletes have a different construction that makes them able to produce up to 25 per cent more energy. Earlier studies show that Q10 is able to improve athletic performance, and it all boils down to optimizing the energy turnover in the cells.

Q10 is a coenzyme that is involved in cellular energy production and protection of our cells. There are numerous cosmetics with Q10 that are believed to delay skin ageing. However, only limited amounts of data have been available to prove the effect of Q10 on skin – until recently.

Women who eat a healthy diet may prevent or delay their physical deterioration. But what type of diet has the best effect? And how can specific nutrients, which are difficult to get from the diet, improve the overall effect?

- but ageing processes and cholesterol-lowering drugs inhibit the body’s Q10 synthesis

No matter how you twist and turn it, cholesterol is an essential substance, and we humans produce most of it ourselves. What is important is to make sure that the cholesterol we have in our blood does not oxidize, and that is something which Q10 and other antioxidants take care of. Stable blood sugar levels also help us maintain a healthy cholesterol balance.

A study has shown that many children and young people suffering from migraines lack coenzyme Q10 and several vitamins. While more research is needed before conclusions can be made, earlier studies have actually shown that Q10 supplementation may have a positive effect on migraine. Because migraine is common among children and adults it is obvious to take a closer look at the underlying cause and compensate for any deficiencies.

Many people suffer from chronic heart failure – often without knowing it. Numerous studies have shown that supplementing with Q10 can improve quality of life and even reduce mortality. An article published in Pharmacologic Therapy reviews the many Q10 studies and makes a point of saying that it is important to choose a Q10 preparation with good bioavailability.

A selenium deficiency may increase the risk of gluten intolerance/celiac disease, which can lead to metabolic disorders and vice versa. Because selenium deficiencies may be a result of eating a poor diet and suffering from malabsorption, this may easily turn into a vicious cycle.

Periodontal disease affects most people at some stage in life. However, according to a recent study that is published in Contemporary Clinical Dentistry, supplemental use of Q10 and tea tree oil may have potential benefits.

A new study links thyroid disorders to female infertility. At the same time, it is known that selenium, an essential micronutrient, is required for normal functioning of the thyroid gland. Modern diets are depleted of selenium and the question is: Could selenium supplements be a good place to begin for infertile couples before embarking on expensive IVF therapy?

The way in which selenium and iodine interact is determining for the thyroid gland and the metabolism. A deficiency of one or both nutrients coupled with exposure to environmental toxins may have grave consequences and contribute to some of the most commonly occurring metabolic disorders.

Although cancer treatments have improved drastically, science has still not managed to break the curve. On the contrary. A growing number of people contract cancer, and that is why we should focus more on the trace element, selenium, which possesses several mechanisms against cancer. However, it requires that we get enough selenium and that is in a form that the body is able to utilize optimally.

If you want to lose weight and/or maintain your ideal weight, it is important to focus on the right proteins, on Q10, and on brown fat cells, as it all boils down to having an effective metabolism and proper energy utilization.

We all get exposed to mercury, a neurotoxin that is found to a great extent in nature and in our environment. According to an EU report, mercury is a large economic burden to society because of the costs related to lowered IQ levels. For that reason alone, we should aim to limit our exposure to mercury and also take a closer look at how selenium protects against the harmful heavy metal - provided our selenium levels are adequately high.

Low selenium status increases a man's risk of prostate cancer and Danish men are particularly susceptible, according to a study published in British Journal of Nutrition. Earlier studies have shown that supplementation with selenium prevents prostate cancer, and selenium yeast has been shown to have the best effect.

A combination of the trace element selenium and the vitamin-like compound coenzyme Q10 appears to be a highly useful treatment for people with impaired cardiac function.

There is only one kind of Q10 with a documented effect

Although there are two forms of coenzyme Q10 in the body - ubiquinone and ubiquinol - only one of them is able to document an effect. This was recently ascertained by one of the leading Q10 researchers in the world.

Studies have shown that sufferers of recurrent migraine headaches may benefit from supplements of the vitamin-like substance coenzyme Q10.

Migraines may be caused by a number of things and cannot be cured as such. A variety of medications have been designed specifically to treat migraines and, in addition, certain drugs that are commonly used to treat other disorders may even help relieve or prevent migraines. However, an increasing number of migraine sufferers seek more natural ways to deal with their recurrent migraine attacks and one remedy that has attracted a substantial amount of interest is the vitamin-like compound coenzyme Q10.

Dr. Yamagishi and colleagues from Japan's University of Tsukuba in a new study has used data from 6,000 middle-aged Japanese, and for the first time have been able to show that low levels of coenzyme Q10 in the blood are strongly associated to an increased risk of disabling dementia.

The researchers took the initiative to this study based on the hypothesis that because coenzyme Q10 has significant antioxidant effects, a high Q10 level ought to lower the risk of developing dementia and vice versa.

More women than men die of cardiovascular disease. Diet and lifestyle play a crucial role in prevention, and there are certain supplements which have been shown to reduce heart-related deaths by over 50%.

The number one heart disease and leading cause of death in Western countries is coronary occlusion, also known as ischemic heart disease. Ischemia translates into "oxygen shortage" and when the heart lacks oxygen due to poor circulation, chest pain (angina pectoris) may occur in connection with physical exertion, cardiac thrombosis, heart failure and sudden death. Because atherosclerosis takes many years to develop it is vital to start early prevention with natural strategies, even before any symptoms are observed.

If you take cholesterol-lowering medicine or if you are a heart failure patient you should definitely continue reading.

Ubiquinone or Ubiquinol - does it really matter? Ever since the discovery of coenzyme Q10 in 1957, scientists have been conducting research with this intriguing nutrient that appears to play a crucial role in human health. Another word for coenzyme Q10 is “ubiquinone” because of its omnipotent importance. “Ubi” means everywhere. In 2006, a new type of CoQ10 called “ubiquinol” surfaced commercially. Clever marketing campaigns attempted to pawn this off as the new and improved CoQ10 source that was absorbed more easily in the body and was superior to ubiquinone. Consumers as well as scientists got confused and started questioning the traditional form of CoQ10 – ubiquinone – although it had been sold commercially and used in studies all along.

Researchers have found that sufferers of non-alcoholic fatty liver disease (NAFLD) can protect themselves by taking the vitamin-like substance coenzyme Q10.

Non-alcoholic fatty liver disease is a chronic liver disorder that involves inflammation of the liver and may worsen through a four-stage progression that may eventually lead to cirrhosis and liver cancer. The condition, which is characterized by a build-up of fat in the liver cells and typically affects people who are diabetic or overweight. There is currently no medical treatment for NAFLD but science has found that the vitamin-like substance coenzyme Q10 may be able to improve the liver's fat metabolism and reduce the inflammation.

Sufferers of multiple sclerosis (MS) who struggle with fatigue symptoms may be helped with a supplement of the vitamin-like compound coenzyme Q10.

Fatigue is one of the most common symptoms of multiple sclerosis (MS) with around 80% of MS sufferers being affected by it, according to the National Multiple Sclerosis Society. It gets worse as the day progresses and the only known medications (amantadine hydrochloride and modafinil) have very limited effect.

This, however, is not the case with the vitamin-like compound, coenzyme Q10, an energy-enhancing and naturally occurring substance that has been seen to help battle symptoms of both fatigue and depression in a study of MS sufferers without causing any side effects.

Okay, yes, we have to admit to ourselves that high blood pressure is a big problem in our society. "The silent killer," the doctors call it.
What about using a well-absorbed Coenzyme Q10 supplement? What might its impact on hypertension be? What, exactly, do we know at present?

Meta-analysis

A good starting point is the meta-analysis done in 2007 by Professor FL Rosenfeldt and his colleagues. They set themselves the task of examining all published results from clinical trials involving the use of Q10 with patients with high blood pressure. They wanted to assess the efficacy and consistency of the Q10 treatment. Furthermore, they wanted to identify any side effects of the Q10 treatment.

Two new studies have shown how the energy-enhancing nutrient, coenzyme Q10, can make the human heart much stronger - even in patients with heart failure.

It can hardly come as a surprise that coenzyme Q10, a widely used energy-enhancing supplement, makes you feel more alert. What is amazing is that two new studies show that it can also give the heart muscle significantly more power. One study was carried out on a normal healthy group of elderly people, while the other study was conducted on heart failure patients. In both studies the heart muscles of the Q10-treated participants obtained significantly more contractile strength - that it its ability to contract - and the number of people who died of cardiovascular complications was reduced by over 50%.

Researchers in central Sweden carried out a most interesting four-year study that involved healthy elderly people. The researchers tested the effects of a daily supplementation of the diet with a combination of a Coenzyme Q10 preparation and a selenium preparation.

Great reduction in cardiovascular deaths

The results of the study were published in 2012 in the International Journal of Cardiology by Professor Urban Alehagen and his team of researchers from the University Hospital in Linköping. The researchers reported, first of all, that there had been a 53% relative reduction in cardiovascular deaths in the treatment group.

Better echocardiograms

Secondly, they reported that the elderly people receiving the active ingredients instead of placebo had had statistically significantly better echocardiograms (meaning better heart function) and statistically significantly lower levels of a peptide in their blood plasma that is a marker for worsening heart failure.

More and more doctors are prescribing more and more statins. Statins do their work by blocking the activity in the liver of the enzyme HMG-CoA, an enzyme that facilitates the synthesis of cholesterol.

Statins and Q10 - same biological pathway

Now we know, from several human and animal studies, that taking statins also inhibits an important step in the body's production of Coenzyme Q10. Dr. Richard Deichmann has summarized the studies that show that CoQ10 deficiency states can result from taking statins.

Taking statins has been associated with reduced levels of CoQ10 in blood serum and in muscle tissue. For example, a study published in the Journal of Clinical Pharmacology has shown that treatment with a statin preparation in a moderate dosage resulted in significantly reduced plasma levels of CoQ10.

Yes, statins are effective at lowering cholesterol levels. There is little doubt about that. But, in common with most prescription medications, statins do have side effects.

The Q-SYMBIO Study

Researchers in nine countries led by the , enrolled 420 patients in a randomized placebo-controlled double-blind clinical trial in which half of the patients were given a 100 mg capsule of Myoqinon Q10, three times daily, and half of the patients were given a placebo capsule, also three times daily.

The patients were all chronic heart failure patients classified as level III (with a marked limitation of physical activity) or level IV (with an inability to carry on any physical activity) in the New York Heart Association's classification scheme.

The age of the patients in years ranged from 50 to 74 years. Nearly all of the of the patients in the study were receiving and continued to receive the standard heart failure medications: angiotensin-converting enzyme inhibitors or angiotensin receptor blockers and beta-blockers.